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Mizzile (ミザイル Mizairu) (Missile in Mega Man for Game Gear) is an missile enemy in Mega Man 5 and Mega Man IV. It basically jumps up from bottomless pits to block shots and interfere with crossing gaps. In Mega Man 5, the Mizzile appears in Napalm Man's military stage and Star Man's space station, while in Mega Man IV, it appears in Napalm Man's Stage and the final level, set on Dr. Wily's spaceship. It is not recommended to destroy them, as they respawn instantly upon being destroyed.

It appears in Napalm Man's and Star Man's Stage again in Mega Man for the Game Gear.  In Mega Man 5,  it is weak to the Super Arrow.

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