In the game, Dr. Froid is manipulated into cooperating with the WWW when his son is held hostage by the organization. Ms. Madd kidnaps his son and blackmails him into freezing the water system in return for his son safety. Lan found his son and was going to tell Dr. Froid about it, but at that time Froid wouldn't listen and insist on attacking Lan and MegaMan. After losing to Lan and MegaMan, Lan was able to relay the good news about his son and he defrosted the towns water supply. After this event, the player can visit him at the Waterworks and challenge him anytime.
Dr. Froid appears again in MegaMan Battle Chip Challenge as a normal contestant that'll be beaten by any playable character.
Dr. Froid in the anime was given a much smaller role, with him being the subject of kidnapping instead of his son. Dr. Froid is kidnapped by Maddy (Ms. Madd), who in turn forces his son to do dirty work for the WWW. Lan and friends discover Dr. Froid tied up when they sneak into the Waterworks after trying to escape a security droid. After being rescued Dr. Froid then asks that Dex and Lan to help him open the valves and for Mayl and Yai to stop Tory. After opening all the valves and hurting himself in the process, the network is repaired and the water supply saved. After the end of the ordeal, Tory and Dr. Froid were reunited. Dr. Froid doesn't appear again afterwards; however, he is mentioned at the beginning of N1 Grand Prix by his son.
- Dr. Froid is the only character from the game that has his role switched with someone else.
- Dr. Froid is one of the few characters that has a mugshot and sprite, that look and is coloured differently that the official artwork.